Author

B. R. Miller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Held· 1 shared B. Avila· 1 shared B. Drouhard· 1 shared B. P. Tu· 1 shared C. K. Wille· 1 shared C. Ye· 1 shared D. W. Lamming· 1 shared D. Yu· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Held

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Author profile →

2 papers

Recent·Most cited

Mechanisms of allosteric and mixed mode aromatase inhibitors

S. A. Souza, A. Held, W. Lu, B. Drouhard, B. Avila, R. Leyva-Montes, M. G. Hu, B. R. Miller, H. L. Ng

This study identifies four novel non-steroidal aromatase inhibitors through virtual screening, showing mixed-type and competitive inhibition with potential for improved adverse effect profiles.

bioRxiv · Oct 15, 2020Biochemistry

Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence

S. A. Haws, D. Yu, C. Ye, C. K. Wille, L. C. Nguyen, K. A. Krautkramer, J. L. Tomasiewicz, S. E. Yang, B. R. Miller, W. H. Liu, K. Igarashi, R. Sridharan, B. P. Tu, V. L. Cryns, D. W. Lamming, J. M. Denu

The paper shows that SAM depletion leads to adaptive chromatin changes that maintain heterochromatin stability and epigenetic persistence in mice.

bioRxiv · Sep 12, 2019Biochemistry