Author

D. W. Lamming

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 5 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 6 Approach:experimental assay· 4 Research Focus:metabolism & bioenergetics· 3 Assay:metabolomics· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

T. A. Hornberger· 2 shared W. G. Zhu· 2 shared A. B. Smith· 1 shared A. E. Schaar· 1 shared A. Greenman· 1 shared A. N. Grossberg· 1 shared A. R. Konopka· 1 shared B. P. Tu· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersPhysiology

T. A. Hornberger

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Author profile →

6 papers

Recent·Most cited

Non-canonical Metabolic and Molecular Effects of Calorie Restriction Are Revealed by Varying Temporal Conditions

H. H. Pak, A. N. Grossberg, R. R. Sanderfoot, R. Babygirija, C. L. Green, M. J. Koller, M. Dzieciatkowska, D. A. Paredes, D. W. Lamming

This study reveals that calorie restriction's effects on metabolism and molecular processes depend on the timing of measurements relative to feeding, not just diet alone.

bioRxiv · Feb 15, 2024Physiology

Quantification of healthspan in aging mice: Introducing FAMY and GRAIL

D. W. Lamming

This paper introduces FAMY and GRAIL, new metrics for quantifying healthspan in aging mice, showing they improve with interventions like calorie restriction and identify protein restriction as a healthspan-promoting intervention.

bioRxiv · Nov 7, 2023Physiology

Resistance exercise protects mice from protein-induced fat accretion

M. E. Trautman, L. N. Braucher, C. Elliehausen, W. G. Zhu, E. Zelenovskiy, M. Green, M. M. Sonsalla, C.-Y. Yeh, T. A. Hornberger, A. R. Konopka, D. W. Lamming

This study shows that high protein diets in mice can enhance muscle growth from resistance exercise without increasing fat mass, but do not improve glycemic control.

bioRxiv · Oct 18, 2022Physiology

Adiponectin receptor agonist AdipoRon improves skeletal muscle function in aged mice

P. Balasubramanian, A. E. Schaar, G. E. Gustafson, A. B. Smith, P. R. Howell, A. Greenman, S. Baum, R. J. Colman, D. W. Lamming, G. M. Diffee, R. Anderson

AdipoRon, an adiponectin receptor agonist, improves skeletal muscle function in aged mice by enhancing mitochondrial activity and metabolism, with effects observed in both mice and nonhuman primates.

bioRxiv · Sep 16, 2021Physiology

Weight Pulling: A Novel Mouse Model of Human Progressive Resistance Exercise

W. G. Zhu, J. E. Hibbert, K. H. Lin, N. D. Steinert, J. L. Lemens, K. W. Jorgenson, S. M. Newman, D. W. Lamming, T. A. Hornberger

This study develops a mouse model of progressive resistance exercise through weight pulling, showing similar muscle adaptations and signaling responses as observed in humans.

bioRxiv · Sep 9, 2021Physiology

Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence

S. A. Haws, D. Yu, C. Ye, C. K. Wille, L. C. Nguyen, K. A. Krautkramer, J. L. Tomasiewicz, S. E. Yang, B. R. Miller, W. H. Liu, K. Igarashi, R. Sridharan, B. P. Tu, V. L. Cryns, D. W. Lamming, J. M. Denu

The paper shows that SAM depletion leads to adaptive chromatin changes that maintain heterochromatin stability and epigenetic persistence in mice.

bioRxiv · Sep 12, 2019Biochemistry