Author

B. P. Tu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Organism:yeast· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

B. M. Sutter· 3 shared B. R. Miller· 1 shared C. K. Wille· 1 shared C. Ye· 1 shared C.-D. Lee· 1 shared D. Liu· 1 shared D. W. Lamming· 1 shared D. Yu· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersCell Biology

B. M. Sutter

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Exonuclease Xrn1 regulates TORC1 signaling in response to SAM availability

M. M. McGinnis, B. M. Sutter, S. Jahangiri, B. P. Tu

This study identifies Xrn1 as a novel regulator of TORC1 signaling in response to methionine starvation, independent of mRNA degradation.

bioRxiv · Sep 28, 2023 · PreprintCell Biology

Pbp1 stabilizes and promotes the translation of Puf3-target mRNAs involved in mitochondrial biogenesis

F. van de Poll, B. M. Sutter, C.-D. Lee, Y.-S. Yang, B. P. Tu

This study shows Pbp1 stabilizes and promotes translation of Puf3-target mRNAs involved in mitochondrial biogenesis under respiratory conditions.

bioRxiv · Sep 14, 2022 · PreprintCell Biology

TMEM120 is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase

J. Xue, Y. Han, H. Baniasadi, W. Zeng, J. Pei, N. Grishin, J. Wang, B. P. Tu, Y. Jiang

The paper presents the cryo-EM structure of TMEM120A, revealing it binds coenzyme A and shares structural features with ELOVL fatty acid elongase, suggesting a potential role in fatty acid metabolism rather than mechanosensation.

bioRxiv · Jun 13, 2021Biophysics

Evidence for a hydrogen sulfide-sensing E3 ligase in yeast

Z. Johnson, Y. Wang, B. M. Sutter, B. P. Tu

The paper identifies how Met30 senses sulfur status through hydrogen sulfide to regulate Met4 ubiquitination and control sulfur amino acid metabolism in yeast.

bioRxiv · Jan 6, 2021Biochemistry

Redox-mediated regulation of a labile, evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain

Y. Lin, X. Zhou, M. Kato, D. Liu, S. Ghaemmaghami, B. P. Tu, S. L. McKnight

This study shows that redox regulation controls TDP43 low complexity domain aggregation into cross-β polymers, with implications for neurodegenerative diseases.

bioRxiv · Dec 24, 2019Biochemistry

Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence

S. A. Haws, D. Yu, C. Ye, C. K. Wille, L. C. Nguyen, K. A. Krautkramer, J. L. Tomasiewicz, S. E. Yang, B. R. Miller, W. H. Liu, K. Igarashi, R. Sridharan, B. P. Tu, V. L. Cryns, D. W. Lamming, J. M. Denu

The paper shows that SAM depletion leads to adaptive chromatin changes that maintain heterochromatin stability and epigenetic persistence in mice.

bioRxiv · Sep 12, 2019Biochemistry