Author

B. Reischl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

O. Friedrich· 4 shared M. Haug· 3 shared C. S. Clemen· 2 shared B. Fabry· 1 shared B. J. Cochran· 1 shared B. Manandhar· 1 shared C. A. Dessalles· 1 shared C. Kopecky· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersPhysiology

O. Friedrich

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4 papers

Recent·Most cited

Effect of insulin insufficiency on ultrastructure and function in skeletal muscle

C. Kopecky, M. Haug, B. Reischl, N. Deshpande, B. Manandhar, T. King, V. Lee, M. Wilkins, M. J. Morris, P. Polly, O. Friedrich, K.-A. Rye, B. J. Cochran

This study investigates how insulin deficiency affects skeletal muscle structure and function in mice with beta-cell dysfunction, finding that insulin supplementation restores muscle integrity and gene expression.

bioRxiv · Dec 18, 2022Physiology

Absence of the Z-disc protein α-actinin-3 impairs the mechanical stability of Actn3KO mouse fast-twitch muscle fibres without altering their contractile properties or twitch kinetics

M. Haug, B. Reischl, S. Nubler, L. Kiriaev, D. A. G. Mazala, P. J. Houweling, K. N. North, O. Friedrich, S. I. Head

bioRxiv · Nov 9, 2021Physiology

The desmin mutation R349P increases contractility and fragility of stem cell-generated muscle micro-tissues

M. Spoerrer, D. Kah, R. C. Gerum, B. Reischl, D. Huraskin, C. A. Dessalles, W. Schneider, W. H. Goldmann, H. Herrmann, I. Thievessen, C. S. Clemen, O. Friedrich, S. Hashemolhosseini, R. Schroeder, B. Fabry

This study shows that the desmin mutation R349P increases contractility and fragility of muscle micro-tissues generated from stem cells, leading to rapid disintegration and mechanical rupture.

bioRxiv · Jul 23, 2021Biophysics

Growing old too early, automated assessment of skeletal muscle single fiber biomechanics in ageing R349P desmin knock-in mice using the MyoRobot technology

C. Meyer, M. Haug, B. Reischl, G. Prölss, T. Pöschel, S. Rupitsch, C. S. Clemen, R. Schröder, O. Friedrich

This study assesses skeletal muscle biomechanics in R349P desmin knock-in mice using MyoRobot technology, finding increased axial stiffness and accelerated shortening in mutant fibers compared to wild-type.

bioRxiv · Aug 19, 2019Physiology