Author

B. J. Cochran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

K.-A. Rye· 4 shared V. Lee· 3 shared B. Manandhar· 2 shared C. Kopecky· 2 shared E. Pandzic· 2 shared M. Wilkins· 2 shared N. Deshpande· 2 shared R. Whan· 2 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersPathology

K.-A. Rye

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Author profile →

4 papers

Recent·Most cited

ApoA-I Protects Pancreatic β-cells from Cholesterol-induced Mitochondrial Damage and Restores their Ability to Secrete Insulin

B. Manandhar, E. Pandzic, N. Deshpande, S.-Y. Chen, V. Wasinger, M. Kockx, E. N. Glaros, K. L. Ong, S. R. Thomas, M. Wilkins, R. Whan, B. J. Cochran, K.-A. Rye

This study shows apoA-I improves β-cell insulin secretion by reducing oxidative stress and enhancing mitochondrial function in cholesterol-loaded cells.

bioRxiv · Apr 3, 2023Cell Biology

Effect of insulin insufficiency on ultrastructure and function in skeletal muscle

C. Kopecky, M. Haug, B. Reischl, N. Deshpande, B. Manandhar, T. King, V. Lee, M. Wilkins, M. J. Morris, P. Polly, O. Friedrich, K.-A. Rye, B. J. Cochran

This study investigates how insulin deficiency affects skeletal muscle structure and function in mice with beta-cell dysfunction, finding that insulin supplementation restores muscle integrity and gene expression.

bioRxiv · Dec 18, 2022Physiology

Use of high-refractive index hydrogels and tissue clearing for large biological sample imaging

A. Richardson, S. Fok, V. Lee, K.-A. Rye, N. Di Girolamo, B. J. Cochran

This study develops high-refractive index hydrogels for stabilizing large biological samples during imaging, enabling effective tissue clearing and light sheet fluorescence microscopy.

bioRxiv · Jan 22, 2020Pathology

Translocator Protein Localises To CD11b+ Macrophages In Atherosclerosis

C. Kopecky, E. Pandzic, A. Parmar, J. Szajer, V. Lee, A. Dupuy, A. Arthur, S. Fok, R. Whan, W. J. Ryder, K.-A. Rye, B. J. Cochran

This study shows TSPO ligand 18F-PBR111 accumulates in atherosclerotic plaques and identifies CD11b+ macrophages as key TSPO-expressing cells during lesion progression.

bioRxiv · Dec 15, 2018Pathology