Author

B. Manandhar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

B. J. Cochran· 2 shared K.-A. Rye· 2 shared M. Wilkins· 2 shared N. Deshpande· 2 shared B. Reischl· 1 shared C. Kopecky· 1 shared E. N. Glaros· 1 shared E. Pandzic· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

B. J. Cochran

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2 papers

Recent·Most cited

ApoA-I Protects Pancreatic β-cells from Cholesterol-induced Mitochondrial Damage and Restores their Ability to Secrete Insulin

B. Manandhar, E. Pandzic, N. Deshpande, S.-Y. Chen, V. Wasinger, M. Kockx, E. N. Glaros, K. L. Ong, S. R. Thomas, M. Wilkins, R. Whan, B. J. Cochran, K.-A. Rye

This study shows apoA-I improves β-cell insulin secretion by reducing oxidative stress and enhancing mitochondrial function in cholesterol-loaded cells.

bioRxiv · Apr 3, 2023Cell Biology

Effect of insulin insufficiency on ultrastructure and function in skeletal muscle

C. Kopecky, M. Haug, B. Reischl, N. Deshpande, B. Manandhar, T. King, V. Lee, M. Wilkins, M. J. Morris, P. Polly, O. Friedrich, K.-A. Rye, B. J. Cochran

This study investigates how insulin deficiency affects skeletal muscle structure and function in mice with beta-cell dysfunction, finding that insulin supplementation restores muscle integrity and gene expression.

bioRxiv · Dec 18, 2022Physiology