Effect of insulin insufficiency on ultrastructure and function in skeletal muscle
C. Kopecky, M. Haug, B. Reischl, N. Deshpande, B. Manandhar, T. King, V. Lee, M. Wilkins, M. J. Morris, P. Polly, O. Friedrich, K.-A. Rye, B. J. Cochran
This study investigates how insulin deficiency affects skeletal muscle structure and function in mice with beta-cell dysfunction, finding that insulin supplementation restores muscle integrity and gene expression.
bioRxiv · Dec 18, 2022Physiology