Identification of cyclic hexapeptides natural products with inhibitory potency against Mycobacterium tuberculosis
S. B. Singh, J. Odingo, M. A. Bailey, B. Sunde, A. Korkegian, T. O'Malley, Y. Ovechkina, T. R. Ioerger, J. C. Sacchettini, K. Young, D. B. Olsen, T. Parish
The paper screens 500 natural products for anti-tubercular activity, identifies five active cyclic hexapeptides, and shows structural analogs lack activity.
bioRxiv · Mar 10, 2018Microbiology