Author

B. W. Doble

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Vujovic· 1 shared C. D. Novina· 1 shared C. E. Joyce· 1 shared D. C. H. Chan· 1 shared J. La Rose· 1 shared J. R. Woodgett· 1 shared J. Xu· 1 shared K. J. Hope· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. Vujovic

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Author profile →

2 papers

Recent·Most cited

Lfc/Arhgef2 regulates mitotic spindle orientation in hematopoietic stem and progenitor cells and is essential for productive hematopoiesis

D. C. H. Chan, A. Vujovic, J. Xu, V. Gordon, N. Wong, L. P. M. H. de Rooij, C. E. Joyce, J. La Rose, M.-J. Sandi, B. W. Doble, C. D. Novina, R. K. Rottapel, K. J. Hope

This study shows that Lfc/Arhgef2 regulates mitotic spindle orientation in HSCs and is essential for hematopoiesis, as its loss causes impaired hematopoietic recovery and HSC exhaustion.

bioRxiv · Nov 27, 2019Cell Biology

Regulation of thymocyte β-selection, development and positive selection by glycogen synthase kinase-3

M. J. Parsons, S. Patel, B. W. Doble, P. S. Ohashi, J. R. Woodgett

This study shows that inactivating GSK-3 and GSK-3β in thymocytes disrupts β-selection and positive selection, leading to T cell developmental defects and lymphomas.

bioRxiv · Jul 24, 2019 · PreprintImmunology