MYCN Amplification and ATRX Mutations are Incompatible in Neuroblastoma
M. Zeineldin, S. Federico, X. Chen…·M. Dyer
The paper shows that ATRX mutations and MYCN amplification are mutually exclusive in neuroblastoma and lead to synthetic lethality.
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M. Zeineldin, S. Federico, X. Chen…·M. Dyer
The paper shows that ATRX mutations and MYCN amplification are mutually exclusive in neuroblastoma and lead to synthetic lethality.
X. Xie, H. Yang, J. J. An…·B. Xu
This study shows that anxiety from BDNF deficiency in specific brain regions increases energy expenditure and reduces diet-induced obesity.
A. R. Marcadis, P. Valderrabano, A. S. Ho…·L. G. T. Morris
This study evaluates the predictive value of ThyroSeq v2 across four institutions for indeterminate thyroid nodules, finding variable positive predictive values and differences in malignancy risk assessment.
This study shows wheat HKT1;5 transporters have dual Na+ affinity and are blocked by K+, with implications for salt tolerance in crops.
Z. Zhang, Z. Zhu, W. Chen…·Y. Peng
The paper curates a database of virus-host receptor interactions and identifies common features of viral receptors, showing their role in cross-species transmission.