Inflammaging in aged tissues drives remodeling of the CD8+ T cell compartment
Irina Shchukina, Carlos J. Rodríguez-Hernández, Heather S. Ruiz, Maksim Kleverov, Rachel L. Mintz, Katsutaka Mineura, Subhadra C. Gunawardana, Sunnie Hsiung, Bishan Bhattarai, Veronika Vachova, Jan Kössl, Denis A. Mogilenko, Rachael L. Field, Tran H. Nguyen, Quazim A. Alayo, , Maxim N. Artyomov
This study shows that inflammaging in aged tissues drives the development of age-associated CD8+ T cells through adipose tissue niches.
Cell Reports · Apr 23, 2026Peer-reviewedImmunology