Author

Carlos J. Rodríguez-Hernández

Institut de Recerca Sant Joan de DéuORCID 0000-0002-5867-3182Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alex Cebria‐XartiD· 2 shared Alexandra AvgustinovaiD· 2 shared Cinzia Emilia LavarinoiD· 2 shared A. Castañeda HerediaiD· 1 shared A. Michel· 1 shared Abel González-PéreziD· 1 shared Alexandre HarariiD· 1 shared Ana Mendizabal-SasietaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenomics

Alex Cebria‐XartORCID

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Author profile →

3 papers

Recent·Most cited

Variable latency between the founder genetic event and rhabdoid tumor expansion

Mònica Sánchez-Guixé, Alex Cebria‐Xart, Naomi Fabre, Carlos J. Rodríguez-Hernández, Morena Pinheiro-Santin, Cinzia Emilia Lavarino, Jarno Drost, Ruben van Boxtel, Núria López-Bigas, Alexandra Avgustinova, Abel González-Pérez

The paper estimates the timing of genetic driver events and clonal expansion in rhabdoid tumors using whole-genome sequencing data from 97 tumors.

bioRxiv · Jul 3, 2026 · PreprintGenomics

Inflammaging in aged tissues drives remodeling of the CD8+ T cell compartment

Irina Shchukina, Carlos J. Rodríguez-Hernández, Heather S. Ruiz, Maksim Kleverov, Rachel L. Mintz, Katsutaka Mineura, Subhadra C. Gunawardana, Sunnie Hsiung, Bishan Bhattarai, Veronika Vachova, Jan Kössl, Denis A. Mogilenko, Rachael L. Field, Tran H. Nguyen, Quazim A. Alayo, , Maxim N. Artyomov

This study shows that inflammaging in aged tissues drives the development of age-associated CD8+ T cells through adipose tissue niches.

Cell Reports · Apr 23, 2026Peer-reviewedImmunology

Spatio-temporal T cell tracking for personalized TCR-T designs in childhood cancer

Inés Sentís, Juan Luis Melero, Alex Cebria‐Xart, M. Grzelak, Marta Soto, A. Michel, Quirze Rovira, Carlos J. Rodríguez-Hernández, Ginevra Caratù, Andrea Urpi, Christophe Sauvage, Ana Mendizabal-Sasieta, Davide Maspero, Cinzia Emilia Lavarino, Anna Pascual Reguant, , Holger Heyn

This study tracks T cell dynamics in a pediatric cancer patient post-ICI therapy to identify tumor-reactive TCRs for personalized TCR-T cell therapy.

Annals of Oncology · May 20, 2025Peer-reviewedGenomics