Author

Batool Shannan

Essen University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Alexander RoeschiD· 2 shared Farnusch KaschaniiD· 2 shared Simon PoepseliD· 2 shared A. Hoewner· 1 shared Alexandra Hommel· 1 shared Alpaslan TasdoganiD· 1 shared Annette PascheniD· 1 shared Barbara T. GrünwaldiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiochemistry

Alexander RoeschORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Differences in substrate engagement and Retinoblastoma protein (RB) binding of human KDM5A and KDM5B

Till Ruengeler, Egor A. Pavlenko, Fabian Basler, Juliane Renn, Farnusch Kaschani, Marie-Anne Derichs, Linda C. Zirden, Batool Shannan, Alexandra Hommel, Markus Kaiser, Alexander Roesch, Simon Poepsel

This study compares the demethylase activity, nucleosome engagement, and RB binding of KDM5A and KDM5B, revealing differences in their interactions and enzymatic behavior.

bioRxiv · May 2, 2026 · PreprintBiochemistry

Redirecting resistance evolution in BRAFV600 melanoma by inhibition of the peroxiredoxin-thioredoxin system

Stefanie Egetemaier, Heike Chauvistré, Renáta Váraljai, Yichao Hua, Smiths Lueong, Samira Makhzami, Nalini Srinivas, Jan Förster, Vivien Ullrich, Simone Stupia, Valéria Schroeder, Sarah Scharfenberg, A. Hoewner, Batool Shannan, Jens Thomas Siveke, , Alexander Roesch

This study identifies KDM5B's role in regulating the PRDX/TXN ROS detoxification system in melanoma DTPs, showing that PRDX inhibition increases ROS vulnerability and delays resistance to MAPK inhibition.

bioRxiv · Mar 10, 2025 · PreprintCancer Biology