Author

A. Hoewner

Essen University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander RoeschiD· 1 shared Alpaslan TasdoganiD· 1 shared Annette PascheniD· 1 shared Barbara T. GrünwaldiD· 1 shared Batool Shannan· 1 shared Björn ScheffleriD· 1 shared Daniel Robert EngeliD· 1 shared Dirk SchadendorfiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander RoeschORCID

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1 paper

Recent·Most cited

Redirecting resistance evolution in BRAFV600 melanoma by inhibition of the peroxiredoxin-thioredoxin system

Stefanie Egetemaier, Heike Chauvistré, Renáta Váraljai, Yichao Hua, Smiths Lueong, Samira Makhzami, Nalini Srinivas, Jan Förster, Vivien Ullrich, Simone Stupia, Valéria Schroeder, Sarah Scharfenberg, A. Hoewner, Batool Shannan, Jens Thomas Siveke, , Alexander Roesch

This study identifies KDM5B's role in regulating the PRDX/TXN ROS detoxification system in melanoma DTPs, showing that PRDX inhibition increases ROS vulnerability and delays resistance to MAPK inhibition.

bioRxiv · Mar 10, 2025 · PreprintCancer Biology