Viral transcriptional regulators extensively rewire host pathways through diverse mechanisms
Jaice T. Rottenberg, Xing Liu, Anna Berenson, Luis F. Soto, Mohamed Yousry ElSadec, Clarissa Stephanie Santoso, James E. Corban, Phillip J. Dexheimer, Berkay Engin, Ryan Lane, Sakshi Shah, Kerstin Spirohn, Shubham Khetan, Cheng-Che Lee, George D. Muñoz-Esquivel, , Juan I. Fuxman Bass
This study systematically profiles 95 viral transcriptional regulators (vTRs) across multiple assays, revealing their diverse mechanisms of rewiring host pathways to promote viral replication and disease links.
bioRxiv · Dec 2, 2025 · PreprintGenomics