Author

Lucía Martínez Cuesta

Boston UniversityORCID 0000-0002-8728-0484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Jaice T. RottenbergiD· 3 shared Juan I. Fuxman BassiD· 3 shared Benedetta D’Elia· 2 shared Berkay Engin· 2 shared Clarissa Stephanie SantosoiD· 2 shared George D. Muñoz-EsquiveliD· 2 shared Luis F. Soto-Ugaldi· 2 shared Mohamed Yousry ElSadec· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersGenomics

Jaice T. RottenbergORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Peptide tiling across viral proteomes identifies modular regulators of stress-induced cell death

Jaice T. Rottenberg, Ezra Taub, Sean Cottrell, Jordyn Choe, Mohamed Yousry ElSadec, Luis F. Soto-Ugaldi, Nicholas W. Harper, Gavin A Birdsall, Kelly M. Ward, Lucía Martínez Cuesta, Clarissa Stephanie Santoso, Philipp Trollmann, Berkay ENGİN, Benedetta D’Elia, David F. Ritter, , Juan I. Fuxman Bass

The paper uses peptide tiling to identify viral protein regions that modulate stress-induced cell death in U2OS cells, revealing modular regulatory functions.

bioRxiv · Aug 4, 2026 · PreprintMicrobiology

Viral transcriptional regulators extensively rewire host pathways through diverse mechanisms

Jaice T. Rottenberg, Xing Liu, Anna Berenson, Luis F. Soto, Mohamed Yousry ElSadec, Clarissa Stephanie Santoso, James E. Corban, Phillip J. Dexheimer, Berkay Engin, Ryan Lane, Sakshi Shah, Kerstin Spirohn, Shubham Khetan, Cheng-Che Lee, George D. Muñoz-Esquivel, , Juan I. Fuxman Bass

This study systematically profiles 95 viral transcriptional regulators (vTRs) across multiple assays, revealing their diverse mechanisms of rewiring host pathways to promote viral replication and disease links.

bioRxiv · Dec 2, 2025 · PreprintGenomics

Global cis-regulatory landscape of double-stranded DNA viruses

Tommy Henry Taslim, Joseph Alexander Finkelberg, Susan Kales, Luis F. Soto-Ugaldi, Benedetta D’Elia, Berkay Engin, George D. Muñoz-Esquivel, Elvis Morara, Jacob Purinton, Harshpreet Chandok, Jaice T. Rottenberg, Rodrigo I. Castro, Lucía Martínez Cuesta, Matias Alejandro Paz, Ryan Tewhey, Juan I. Fuxman Bass

The paper identifies ~2,000 cis-regulatory elements (CREs) across 27 dsDNA viruses using reporter assays and machine learning, revealing their regulatory features and associated transcription factors.

bioRxiv · Jul 20, 2025 · PreprintGenomics