Sakshi Shah

Multilayered specificity of transcription factor binding at cytokine promoters

The paper identifies TF-DNA binding interactions at cytokine promoters, showing that TF cooperativity and antagonism significantly influence DNA-binding specificity.

Viral transcriptional regulators extensively rewire host pathways through diverse mechanisms

This study systematically profiles 95 viral transcriptional regulators (vTRs) across multiple assays, revealing their diverse mechanisms of rewiring host pathways to promote viral replication and disease links.

A large-scale cancer-specific protein-DNA interaction network

This study constructs a large-scale cancer-specific TF-DNA interaction network and identifies potential therapeutic targets among oncogenes and TFs.

Paired yeast one-hybrid assays to detect DNA-binding cooperativity and antagonism across transcription factors

The paper introduces paired yeast one-hybrid assays to detect DNA-binding cooperativity and antagonism between transcription factors and demonstrates their application across various TF pairs.