Luis F. Soto

Systemic Autoimmunity Remodels Microbiota-Reactive CD4⁺ T Cell Immunity

This study shows systemic autoimmunity expands and differentiates microbiota-reactive CD4 T cells, which exacerbate autoimmunity through IL-21 and IFN-gamma mechanisms.

Viral transcriptional regulators extensively rewire host pathways through diverse mechanisms

This study systematically profiles 95 viral transcriptional regulators (vTRs) across multiple assays, revealing their diverse mechanisms of rewiring host pathways to promote viral replication and disease links.

A large-scale cancer-specific protein-DNA interaction network

This study constructs a large-scale cancer-specific TF-DNA interaction network and identifies potential therapeutic targets among oncogenes and TFs.

Epitope-Evaluator: an interactive web application to study predicted T-cell epitopes

Epitope-Evaluator is a web tool that allows users to interactively analyze and filter predicted T-cell epitopes from immunoinformatic tools.