Author

Birgitte Walgreen

Radboud University Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

E.L. VittersiD· 3 shared A. van CaamiD· 2 shared Daphne N. DorstiD· 2 shared Hans J. P. M. KoeneniD· 2 shared Peter M van der Kraan· 2 shared Rogier M. ThurlingsiD· 2 shared Theodoros Ioannis PapadimitriouiD· 2 shared A. Essen· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

E.L. VittersORCID

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3 papers

Recent·Most cited

Imaging guided single-cell multiomics unveils shared autoreactive CD4+ T-cell responses in blood, locoregional lymph node and affected tissues of patients with systemic autoimmunity

Theodoros Ioannis Papadimitriou, Prashant Singh, Arjan van Caam, Xuehui He, Konnie M. Hebeda, Birgitte Walgreen, E.L. Vitters, Pim Kloosterman, Laura J. A. Wingens, Klaas W. Mulder, Madelon C Vonk, I. Jolanda de Vries, Peter M van der Kraan, Ruben L. Smeets, Erik H.J.G. Aarntzen, , Rogier M. Thurlings

The paper uses imaging-guided single-cell multiomics to identify shared autoreactive CD4+ T-cell responses in blood, lymph nodes, and tissues of patients with systemic autoimmune diseases.

bioRxiv · Aug 23, 2026 · PreprintImmunology

MONOCYTES STRONGLY INDUCE (MYO)FIBROBLAST CONTRACTION IN A NEW 3D SKIN MODEL TO UNDERSTAND THE INFLAMMATION-FIBROSIS AXIS IN SYSTEMIC SCLEROSIS

Djúlio César Zanin-Silva, Nienke J T van Kooten, Theogiannis I. Papadimitriou, Daphne N. Dorst, Birgitte Walgreen, E.L. Vitters, M. H. J. van den Bosch, Marije Koenders, A. van Caam

This study uses a 3D skin model to show that monocytes and macrophages induce myofibroblast contraction via JAK/STAT3 and TGF-β signaling in systemic sclerosis.

bioRxiv · Feb 14, 2026 · PreprintImmunology

CD8+ T cells drive myofibroblast activation and contraction via JAK/STAT3 and TGFβ signaling

Theodoros Ioannis Papadimitriou, A. Essen, Merel Willemse, Daphne N. Dorst, E.L. Vitters, Birgitte Walgreen, Hans J. P. M. Koenen, Peter M van der Kraan, Marije I. Koenders, Rogier M. Thurlings, A. van Caam

This study shows CD8+ T cells drive myofibroblast activation and contraction through JAK/STAT3 and TGFβ signaling, not cytotoxicity, and suggests combined inhibition of these pathways could treat fibrosis.

iScience · Oct 30, 2025Peer-reviewedImmunology