Author

Blaine J. Loughlin

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Andrew S. PaigeiD· 1 shared Anita BalázsiD· 1 shared Cédric GovaertsiD· 1 shared David N. SheppardiD· 1 shared James N. CharlickiD· 1 shared John C. KappesiD· 1 shared John Francis HuntiD· 1 shared Marcus Alexander MalliD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Andrew S. PaigeORCID

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1 paper

Recent·Most cited

Correcting mutant CFTR with a stabilizing nanobody reveals a novel active conformation of the channel

Marie Overtus, James N. Charlick, Tihomir Rubil, Andrew S. Paige, Blaine J. Loughlin, Zachary Rich, Mayuree Rodrat, Zhengrong Yang, Anita Balázs, John C. Kappes, Marcus Alexander Mall, David N. Sheppard, John Francis Hunt, Cédric Govaerts

This study uses a nanobody to stabilize mutant CFTR, revealing a novel active conformation and improving its function in cystic fibrosis.

bioRxiv · Oct 8, 2025 · PreprintBiochemistry