Author

Anita Balázs

German Center for Lung ResearchORCID 0000-0002-1402-5239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Cédric GovaertsiD· 2 shared Marcus Alexander MalliD· 2 shared Marie OvertusiD· 2 shared Tihomir RubiliD· 2 shared Andrew S. PaigeiD· 1 shared Blaine J. Loughlin· 1 shared Christian P. R. HackenbergeriD· 1 shared David N. SheppardiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBiochemistry

Cédric GovaertsORCID

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2 papers

Recent·Most cited

A Cell-Permeable Nanobody to Restore F508del Cystic Fibrosis Transmembrane Conductance Regulator Activity

Luise Franz, Tihomir Rubil, Anita Balázs, Marie Overtus, Kristin Kemnitz‐Hassanin, Cédric Govaerts, Marcus Alexander Mall, Christian P. R. Hackenberger

This paper develops a cell-permeable nanobody to restore function of the misfolded F508del-CFTR protein in CF bronchial epithelial cells.

Nature Chemical Biology · Apr 17, 2026Peer-reviewedBiochemistry

Correcting mutant CFTR with a stabilizing nanobody reveals a novel active conformation of the channel

Marie Overtus, James N. Charlick, Tihomir Rubil, Andrew S. Paige, Blaine J. Loughlin, Zachary Rich, Mayuree Rodrat, Zhengrong Yang, Anita Balázs, John C. Kappes, Marcus Alexander Mall, David N. Sheppard, John Francis Hunt, Cédric Govaerts

This study uses a nanobody to stabilize mutant CFTR, revealing a novel active conformation and improving its function in cystic fibrosis.

bioRxiv · Oct 8, 2025 · PreprintBiochemistry