Deciphering Ibogaines Matrix Pharmacology: Multiple Transporter Modulation at Serotonin Synapses
Christopher Hwu, Václav Havel, Xavier O. Westergaard, Adriana M. Mendieta, Inis C. Serrano, Jennifer Hwu, Donna M. Walther, David Lankri, Tim Luca Selinger, Keer He, R. Liu, Tyler P Shern, Steven Sun, Boxuan Ma, Bruno González, , Dalibor Sameš
This study investigates how ibogaine and its metabolite noribogaine modulate monoamine transporters, revealing their unique pharmacological profile and explaining their therapeutic effects.
Journal of the American Chemical Society · Dec 26, 2025Peer-reviewedNeuroscience