Persistent cortical excitatory neuron dysregulation in adult Chd8 haploinsufficient mice.
César P. Canales, Stephanie A. Lozano, Nicholas Alonzo Frost, Karol Cichewicz, Wellington Z. Amaral, Nicolas Seban, Ethan Fenton, A. Ayanna Wade, Nickolas Chu, Emily M. Smith, Cory S. Ardekani, Samuel Frank, Jeffrey Bennett, Pierre Lavenex, Aspen Kopley-Smith, , Alex S. Nord
This study identifies persistent excitatory neuron dysfunction in Chd8 haploinsufficient mice through single nucleus transcriptomics and behavioral analysis.
bioRxiv · Jun 4, 2025 · PreprintGenomics