Author

Emily M. Smith

University of California, DavisORCID 0000-0002-8651-9174Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Emily Smith5 papers · Emory University

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alex S. NordiD· 3 shared César P. CanalesiD· 3 shared Aspen Kopley-SmithiD· 2 shared Daniela Perla· 2 shared Darlene RahbarianiD· 2 shared Ethan Fenton· 2 shared Karol CichewicziD· 2 shared Nicolas SebaniD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersMolecular Biology

Alex S. NordORCID

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Author profile →

3 papers

Recent·Most cited

Molecular interactions of Chd8 in mouse brain highlights a role in chromatin-associated RNA processing

Emily Smith, César P. Canales, Mathew W. Kenaston, Nicolas Seban, Ayanna A. Wade, Ethan Fenton, Cory Ardekani, Stephanie Lozano, Nickolas C. Chu, Daniela Perla, Ksenia Medvedeva, Kaitlyn McCafferty, Yingjing Guo, Aspen Kopley-Smith, Abigail Ignasiak, , Alex S. Nord

The paper identifies CHD8 interactions in mouse brain, revealing a role in chromatin-associated RNA processing and highlighting dosage sensitivity in neurodevelopmental disorders.

bioRxiv · Dec 12, 2025 · PreprintMolecular Biology

Persistent cortical excitatory neuron dysregulation in adult Chd8 haploinsufficient mice.

César P. Canales, Stephanie A. Lozano, Nicholas Alonzo Frost, Karol Cichewicz, Wellington Z. Amaral, Nicolas Seban, Ethan Fenton, A. Ayanna Wade, Nickolas Chu, Emily M. Smith, Cory S. Ardekani, Samuel Frank, Jeffrey Bennett, Pierre Lavenex, Aspen Kopley-Smith, , Alex S. Nord

This study identifies persistent excitatory neuron dysfunction in Chd8 haploinsufficient mice through single nucleus transcriptomics and behavioral analysis.

bioRxiv · Jun 4, 2025 · PreprintGenomics

Hyperexcitability and translational phenotypes in a preclinical model of SYNGAP1 mutations

Timothy A. Fenton, Olivia Y Haouchine, Elizabeth L Hallam, Emily M. Smith, Kiya C. Jackson, Darlene Rahbarian, César P. Canales, Anna Adhikari, Alex S. Nord, Roy Ben‐Shalom, Jill L. Silverman

This paper investigates functional impairments in Syngap1 mutant mice, identifying translational biomarkers in both in vitro and in vivo neurophysiological data.

bioRxiv · Jul 24, 2023 · PreprintNeuroscience