SUMO2 Promotes Histone Pre-mRNA Processing by Stabilizing Histone Locus Body Interactions and Facilitating U7 snRNP Assembly
Shuying He, Pin Lyu, Marnie W. Skinner, Anthony W. Desotell, Brendan Foley, Chance M McCaig, Wei Wang, Qian Jiang, Liang Tong, William F. Marzluff, Michael J. Matunis
This study shows SUMO2 stabilizes HLB interactions and facilitates U7 snRNP assembly, preventing histone mRNA polyadenylation.
Genes & Development · Jul 10, 2025Peer-reviewedMolecular Biology