Author

Brennen Keuchel

Vanderbilt University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1

Frequent Co-Authors

Eric K.F. DonahueiD· 2 shared Kristopher BurkewitziD· 2 shared Aaron Orgel· 1 shared Alexandra G. MulliganiD· 1 shared D. J. Johnson· 1 shared Jason A. MacGurniD· 1 shared Kelsey N MabryiD· 1 shared Mark H. EllismaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Eric K.F. DonahueORCID

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2 papers

Recent·Most cited

ER discontinuities are common in C. elegans neurons, revealing a genetically tractable model for ER network maintenance

Kelsey N Mabry, Eric K.F. Donahue, Aaron Orgel, Brennen Keuchel, Max Kushner, Kristopher Burkewitz

The paper shows that ER discontinuities are common in healthy C. elegans neurons and links their frequency to age, stress, and ER shaping factors.

bioRxiv · Apr 2, 2026 · PreprintCell Biology

ER-phagy drives age-onset remodeling of endoplasmic reticulum structure-function and lifespan

Eric K.F. Donahue, Nathaniel L. Hepowit, Brennen Keuchel, Alexandra G. Mulligan, D. J. Johnson, Mark H. Ellisman, Rafael Arrojo e Drigo, Jason A. MacGurn, Kristopher Burkewitz

This study shows that ER-phagy drives age-related ER remodeling and lifespan, revealing it as a protective mechanism in aging.

bioRxiv · Aug 7, 2024 · PreprintCell Biology