Kristopher Burkewitz

This study uses MIMS-EM to analyze metabolic turnover in C. elegans during dietary restriction, revealing tissue- and resource-specific changes at multiple scales.

The paper shows that ER discontinuities are common in healthy C. elegans neurons and links their frequency to age, stress, and ER shaping factors.

This study identifies InsP3R signaling as a mediator of mitochondrial stress-induced longevity in C. elegans through actomyosin-dependent mitochondrial dynamics.

This study identifies nutrient-responsive mitochondrial-derived structures in C. elegans muscle cells induced during refeeding, revealing a role in mitochondrial remodeling and metabolic adaptation.

This study shows that ER-phagy drives age-related ER remodeling and lifespan, revealing it as a protective mechanism in aging.

The paper identifies Ribosome-Associated Vesicles (RAVs) as dynamic platforms that facilitate activity-dependent local translation in neurons by transporting ribosomes to distal processes.