Reciprocal macrophage-MSC crosstalk drives immunomodulatory and regenerative phenotypes in a mineralized collagen scaffold
Vasiliki Kolliopoulos, Maxwell Polanek, Hashni Epa Vidana Gamage…·Brendan A.C. Harley
This study shows that MSC-macrophage interactions in a mineralized collagen scaffold drive immunomodulatory and regenerative responses through IL-6 secretion and M2-like macrophage polarization.