Author

H. F. Kuipers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Hargil· 3 shared G. Kaber· 3 shared N. Nagy· 3 shared K. Yadava· 2 shared P. L. Bollyky· 2 shared P. L. Marshall· 2 shared T. N. Wight· 2 shared A. Kosters· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

A. Hargil

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Author profile →

4 papers

Recent·Most cited

Inhibition of hyaluronan synthesis prevents β-cell loss in obesity-associated type 2 diabetes

N. Nagy, G. Kaber, V. Sunkari, P. L. Marshall, A. Hargil, H. F. Kuipers, H. Ishak, M. Bogdani, R. Hull, M. Grandoch, J. Fischer, T. McLaughlin, T. Wight, P. Bollyky

This study shows that inhibiting hyaluronan synthesis with 4-MU prevents β-cell loss in obesity-associated type 2 diabetes by increasing survivin expression and blocking apoptosis.

bioRxiv · Feb 28, 2023Immunology

FOXP3+ regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues

H. A. Martinez, I. Koliesnik, G. Kaber, N. Nagy, G. Barlow, B. A. Falk, J. K. Reid, C. O. Medina, A. Hargil, I. Vlodavsky, J.-p. Li, M. Perez-Cruz, S.-W. Tang, E. H. Meyer, L. E. Wrenshall, , H. F. Kuipers

The paper shows FOXP3+ Treg use heparanase to access IL-2 bound to ECM in inflamed tissues, enhancing their function and stability.

bioRxiv · Feb 26, 2023Immunology

Hematopoietic stem cell requirement for macrophage regeneration is tissue-specific

D. J. Eddins, A. Kosters, J. Waters, J. Sosa, M. Phillips, K. Yadava, L. A. Herzenberg, H. F. Kuipers, E. Ghosn

The paper shows that hematopoietic stem cells (HSCs) are required for regeneration of peritoneal macrophages but not brain microglia.

bioRxiv · Apr 8, 2021Immunology

Hyaluronan Synthesis Inhibition Impairs Antigen Presentation and Delays Transplantation Rejection

P. L. Marshall, N. Nagy, G. Kaber, G. L. Barlow, A. Ramesh, B. J. Xie, M. H. Linde, N. L. Haddock, C. A. Lester, Q.-L. Tran, C. R. de Vries, A. Malkovskiy, I. Gurevich, H. Martinez, H. F. Kuipers, , P. L. Bollyky

This study shows that inhibiting hyaluronan synthesis with 4MU impairs antigen presentation and delays transplant rejection in mice and human T-cell reactions.

bioRxiv · Aug 28, 2020Immunology