Author

C. A. Williams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Knupp· 1 shared A. S. T. Smith· 1 shared A. T. Lehrer· 1 shared B. K. Haun· 1 shared C. E. Murry· 1 shared C. Kinoshita· 1 shared C.-Y. Lai· 1 shared D. L. Mack· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperCell Biology

A. Knupp

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Perpendicular Shear Stresses Drive Transmural Helical Remodeling in Engineered Human Ventricular Models

N. P. Williams, K. M. Beussman, J. R. Foster, M. Rhodehamel, C. A. Williams, J. H. Tsui, A. S. T. Smith, D. L. Mack, C. E. Murry, N. J. Sniadecki, D.-H. Kim

This study shows that perpendicular shear stress drives helical transmural remodeling in engineered human ventricles, revealing how physical forces influence cardiac architecture.

bioRxiv · Aug 18, 2022 · PreprintBioengineering

The Alzheimer's gene SORL1 is a key regulator of endosomal traffic and recycling in human neurons

S. Mishra, A. Knupp, M. Szabo, C. A. Williams, C. Kinoshita, D. W. Hailey, Y. Wang, J. E. Young

This study shows SORL1 regulates endosomal recycling in neurons by affecting APP, TRKB, and GLUA1 trafficking, with implications for Alzheimer's disease.

bioRxiv · Jul 26, 2021Cell Biology

CoVaccine HT™ adjuvant potentiates robust immune responses to recombinant SARS-CoV-2 Spike S1 immunisation

B. K. Haun, C.-Y. Lai, C. A. Williams, T. A. S. Wong, M. M. Lieberman, L. Pessaint, H. A. Elyard, A. T. Lehrer

This study evaluates the adjuvant CoVaccine HT in SARS-CoV-2 Spike S1 vaccines, showing it enhances IgG titres, affinity maturation, class switching, and cell-mediated immunity compared to Alhydrogel.

bioRxiv · Jul 24, 2020Immunology

Whole genome sequencing of Herpes Simplex Virus 1 directly from human cerebrospinal fluid reveals selective constraints in neurotropic viruses.

F. Lassalle, M. A. Beale, T. Bharucha, C. A. Williams, R. J. Williams, J. Cudini, R. A. Goldstein, T. Haque, D. P. Depledge, J. Breuer

This study uses whole genome sequencing of HSV-1 from CSF and skin lesions to identify selective constraints and recombination patterns in neurotropic viruses.

bioRxiv · Dec 6, 2019Evolutionary Biology