Author

C. Antonescu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

A. Blackford· 1 shared A. Desrichard· 1 shared A. Eisenberg· 1 shared A. Henssen· 1 shared A. Ho· 1 shared A. Kentsis· 1 shared A.-K. Emde· 1 shared C. Mason· 1 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Blackford

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3 papers

Recent·Most cited

Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs

F. Fekri, J. Abousawan, S. J. Bautista, R. M. Dayam, C. Antonescu, R. Karshafian

This study shows that ultrasound and microbubble treatments enhance flotillin-dependent endocytosis, improving drug uptake and efficacy of cisplatin in cancer cells.

bioRxiv · Feb 7, 2019Cell Biology

Multi-dimensional genomic analysis of myoepithelial carcinoma identifies prevalent oncogenic gene fusions

M. Dalin, N. Katabi, M. Persson, K.-W. Lee, V. Makarov, A. Desrichard, L. Walsh, L. West, Z. Nadeem, D. Ramaswami, J. Havel, F. Kuo, K. Chadalavada, G. Nanjangud, N. Riaz, , L. G. T. Morris

This study identifies prevalent oncogenic gene fusions in myoepithelial carcinoma through genomic analysis, highlighting TGFBR3-PLAG1 as a key fusion and potential therapeutic target.

bioRxiv · Jun 9, 2017Cancer Biology

Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors

A. Henssen, R. Koche, J. Zhuang, E. Jiang, C. Reed, A. Eisenberg, E. Still, I. MacArthur, E. Rodriguez-Fos, S. Gonzalez, M. Puiggros, A. Blackford, C. Mason, E. De Stanchina, M. Gonen, , A. Kentsis

This study identifies PGBD5 as an oncogenic DNA transposase in rhabdoid tumors, causing site-specific genomic rearrangements through PSS sequences and end-joining repair.

bioRxiv · Feb 23, 2017Cancer Biology