Author

S. J. Bautista

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

C. N. Antonescu· 2 shared A. Vissa· 1 shared A.-C. Gingras· 1 shared C. Antonescu· 1 shared C. M. Yip· 1 shared D. Schwendener Forkel· 1 shared F. Fekri· 1 shared G. Hesketh· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

C. N. Antonescu

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3 papers

Recent·Most cited

Control of GSK3beta nuclear localization by amino acid signaling requires GATOR1 but is mTORC1 independent

D. Schwendener Forkel, O. Ibazebo, S. Soha, S. J. Bautista, S. Impellizzeri, R. J. Botelho, G. Hesketh, A.-C. Gingras, C. N. Antonescu

The paper shows that GATOR1 regulates GSK3β nuclear localization in response to amino acids, independent of mTORC1, and that this process supports cell survival under metabolic stress.

bioRxiv · Apr 9, 2024 · PreprintCell Biology

Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs

F. Fekri, J. Abousawan, S. J. Bautista, R. M. Dayam, C. Antonescu, R. Karshafian

This study shows that ultrasound and microbubble treatments enhance flotillin-dependent endocytosis, improving drug uptake and efficacy of cisplatin in cancer cells.

bioRxiv · Feb 7, 2019Cell Biology

mTORC1 controls glycogen synthase kinase 3β nuclear localization and function

S. J. Bautista, I. Boras, A. Vissa, N. Mecica, C. M. Yip, P. K. Kim, C. N. Antonescu

The paper shows mTORC1 inhibits GSK3β nuclear localization and function, linking metabolic signals to transcriptional control of biomass production.

bioRxiv · Mar 6, 2018Cell Biology