Author

R. Karshafian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Approach:graph neural network· 1 Assay:metabolomics· 1

Frequent Co-Authors

C. N. Antonescu· 2 shared A. Haller· 1 shared A. Windemuth· 1 shared B. Wang· 1 shared C. Antonescu· 1 shared D. S. Redka· 1 shared E. Rujas· 1 shared F. Fekri· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

C. N. Antonescu

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3 papers

Recent·Most cited

AMP-activated protein kinase (AMPK) is required for recovery from metabolic stress induced by ultrasound microbubble treatment

L. Lo, O. Uchenunu, R. J. Botelho, C. N. Antonescu, R. Karshafian

This study investigates how AMPK mediates cellular recovery from metabolic stress caused by ultrasound microbubble treatment in breast cancer cells.

bioRxiv · Mar 2, 2022Cell Biology

Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease

M. Sugiyama, H. Cui, D. S. Redka, M. Karimzadeh, E. Rujas, H. Maan, S. Hayat, K. Cheung, R. Misra, J. B. McPhee, R. D. Viirre, A. Haller, R. Botelho, R. Karshafian, S. A. Sabatinos, , C. N. Antonescu

bioRxiv · Apr 13, 2021Cell Biology

Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs

F. Fekri, J. Abousawan, S. J. Bautista, R. M. Dayam, C. Antonescu, R. Karshafian

This study shows that ultrasound and microbubble treatments enhance flotillin-dependent endocytosis, improving drug uptake and efficacy of cisplatin in cancer cells.

bioRxiv · Feb 7, 2019Cell Biology