Author

C. B. Howard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 5 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:proteomics· 5 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Organism:human· 2 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

B. L. Schulz· 4 shared L. F. Zacchi· 4 shared C. L. Pegg· 3 shared D. Roche Recinos· 3 shared C. Aitken· 2 shared T. K. Phung· 2 shared V. Sandford· 2 shared Y. Y. Lee· 2 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

B. L. Schulz

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Application of chimeric antigens to paper-based diagnostics for detection of West Nile virus infections of Crocodylus porosus: a novel animal test case

R. A. Johnston, G. Habarugira, J. J. Harrison, S. R. Isberg, J. Moran, M. Morgan, S. S. Davis, L. F. Melville, C. B. Howard, C. S. Henry, J. Macdonald, H. A. Bielefeldt-Ohmann, R. A. Hall, J. Hobson-Peters

The paper develops a lateral flow assay using chimeric antigens to detect West Nile virus seroconversion in crocodiles, achieving 100% sensitivity and specificity.

bioRxiv · Mar 24, 2024 · PreprintBiochemistry

Cell Width in Escherichia coli: Interrogating Coupling to Nucleoid Structure

A. Zaritsky, C. B. Howard, G. Yehezkel, A. Rabinovitch

The paper investigates how nucleoid complexity influences cell width in Escherichia coli by analyzing the relationship between replication and growth rates.

bioRxiv · May 15, 2023Microbiology

Analysis of coagulation factor IX in bioreactor cell culture medium predicts yield and quality of the purified product

L. F. Zacchi, D. Roche Recinos, C. L. Pegg, T. K. Phung, M. Napoli, C. Aitken, V. Sandford, S. M. Mahler, Y. Y. Lee, B. L. Schulz, C. B. Howard

The paper uses DIA-MS proteomics to predict rFIX yield and quality by analyzing bioreactor supernatant, identifying PTMs and their impact on purification and function.

bioRxiv · Jun 3, 2020Biochemistry

Identification of novel glycosylation events on human serum-derived Factor IX

C. L. Pegg, L. F. Zacchi, D. Roche Recinos, C. B. Howard, B. L. Schulz

The paper identifies two novel glycosylation sites on human Factor IX, including an O-linked site at serine 141 and an N-linked site at asparagine 258, contributing to structural characterization for therapeutic development.

bioRxiv · Mar 6, 2020Biochemistry

S-Trap eliminates cell culture media polymeric surfactants for effective proteomic analysis of mammalian cell bioreactor supernatants

L. F. Zacchi, D. Roche Recinos, E. Otte, C. Aitken, T. Hunt, V. Sandford, Y. Y. Lee, B. L. Schulz, C. B. Howard

This study compares sample preparation methods to remove polymeric surfactants from bioreactor supernatants, finding S-Trap provides the best clean-up and data quality.

bioRxiv · Feb 17, 2020Biochemistry

Glycoproteomic measurement of site-specific polysialylation

R. Pelingon, C. L. Pegg, L. F. Zacchi, T. K. Phung, C. B. Howard, P. Xu, M. P. Hardy, C. M. Owczarek, B. L. Schulz

This paper develops a high-throughput glycoproteomics method to measure site-specific polysialylation using LC-ESI-MS/MS after mild acid hydrolysis and desialylation.

bioRxiv · Jan 21, 2020Biochemistry