Author

C. B. Thompson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

X. Cai· 2 shared A. Bender· 1 shared A. M. Bilate· 1 shared A. S. Pereyra· 1 shared A. Santella· 1 shared B. Hurwitz· 1 shared B. Stauffer· 1 shared C. Argmann· 1 shared

Activity by Year

2022-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCell Biology

X. Cai

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Lactate activates the mitochondrial electron transport chain independent of its metabolism

X. Cai, C. C. Ng, O. Jones, T. S. Fung, K. Ryu, D. Li, C. B. Thompson

This study shows lactate activates the mitochondrial electron transport chain without being metabolized, suppressing glycolysis and enhancing oxidative phosphorylation in various cell types.

bioRxiv · Aug 2, 2023 · PreprintCell Biology

A tissue injury repair pathway distinct but parallel to host pathogen defense

S. Liu, Y. H. Hur, X. Cai, Q. Cong, Y. Yang, C. Xu, A. M. Bilate, K. A. U. Gonzales, C. J. Cowley, B. Hurwitz, J.-D. Luo, T. Tseng, S. Gur-Cohen, M. Sribour, T. Omelchenko, , E. Fuchs

This study identifies IL24 as a tissue repair pathway parallel to IFN-mediated host defense, showing its role in epithelial and mesenchymal regeneration after injury.

bioRxiv · Oct 18, 2022 · PreprintImmunology

Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting tumor mutation burden

J. M. Schvartzman, G. C. Forsyth, H. Walch, W. Chatila, A. Santella, K. Menghrajani, F. Sanchez-Vega, R. Koche, C. B. Thompson

This study shows that IDH mutations cause replication stress through heterochromatin, affecting DNA repair and PARP inhibitor response without increasing mutation burden.

bioRxiv · Aug 4, 2022 · PreprintCancer Biology

Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines

S. Schwörer, M. Ros, K. M. Tsanov, F. V. Cimino, S. W. Lowe, C. Carmona-Fontaine, C. B. Thompson

The paper shows hypoxia enhances the inflammatory fibroblast phenotype in pancreatic cancer through HIF-1 activation, promoting tumor progression.

bioRxiv · Jul 26, 2022Cell Biology

A mitochondrial long-chain fatty acid oxidation defect leads to uncharged tRNA accumulation and activation of the integrated stress response in the mouse heart

P. Ranea-Robles, N. N. Pavlova, A. Bender, A. S. Pereyra, J. M. Ellis, B. Stauffer, C. Yu, C. B. Thompson, C. Argmann, M. A. Puchowicz, S. M. Houten

Cardiovascular Research · Apr 7, 2022Peer-reviewedPhysiology