Author

C. Bueno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Plant Biology· 2 Bioengineering· 1 Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Research Focus:development & morphogenesis· 4 Approach:deep learning· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Organism:plant (other)· 2

Frequent Co-Authors

P. Menendez· 3 shared A. Bataller· 2 shared A. J. Domingo· 2 shared B. Clerget· 2 shared H. Heyn· 2 shared J. L. Trincado· 2 shared A. B. De Nardi· 1 shared A. Bigas· 1 shared

Activity by Year

2019-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersImmunology

P. Menendez

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Author profile →

9 papers

Recent·Most cited

PyTorch Frustratometer: An Ultra-fast, Parallelized Tool for Proteome-Scale Local Energetic Frustration Analysis

E. J. Draizen, H. Jaafari, C. Bueno, A. Llaberia, F. Clark, E. A. Galpern, F. L. Simonetti, M. I. Freiberger, P. G. Wolynes, D. U. Ferreiro, R. Gonzalo Parra

The paper introduces a PyTorch-based tool for fast proteome-scale local frustration analysis, achieving 70-13,000x speedup over the original FrustratometeR.

bioRxiv · Nov 9, 2026 · PreprintBioinformatics

Integrative single-cell multi-omics of CD19CARpos and CARneg T cells suggest drivers of immunotherapy response in B-cell neoplasias

M. Guerrero-Murillo, A. Rill-Hinarejos, J. L. Trincado, A. Bataller, V. Ortiz-Maldonado, D. Benitez-Ribas, M. Espanol, E. A. Gonzalez, N. Martinez-Cibrian, D. Marchese, L. Martin-Martin, A. M. Garcia-Sancho, H. Heyn, M. Juan, A. Urbano-Ispizua, , P. Menendez

This study integrates single-cell multi-omics data from CAR-T cells to identify factors influencing immunotherapy response in B-cell neoplasias.

bioRxiv · Jan 23, 2024 · PreprintImmunology

Towards Generalizability and Robustness in Biological Object Detection in Electron Microscopy Images

K. GIANNIOS, A. Chaurasia, C. Bueno, J. L. Riesterer, L. Pagano, T. P. Lo, G. Thibault, J. W. Gray, X. Song, B. DeLaRosa

This study improves model generalizability in biological object detection using electron microscopy images through normalization and augmentation techniques, achieving a 29% average precision boost.

bioRxiv · Nov 27, 2023 · PreprintBioengineering

Chromatin activity of IκBα mediates the exit from naïve pluripotency

L. G. Palma, D. Alvarez-Villanueva, M. Maqueda, M. Barrero, A. IGLESIAS, j. Bertran, D. ALVAREZ, C. GARCIA-PRIETO, C. BALLARE, V. RODRIGUEZ-CORTEZ, C. BUENO, A. VIDAL, A. Villanueva, P. Menendez, G. Stik, , A. Bigas

This study shows that IκBα's chromatin activity, not its NF-κB signaling role, is critical for exiting naïve pluripotency in embryonic stem cells.

bioRxiv · Jul 28, 2023Cell Biology

The nuclei of human adult stem cells can move within the cell and generate cellular protrusions to contact other cells

C. Bueno, D. Garcia-Bernal, S. Martinez, M. Blanquer, J. M. Moraleda

This study shows that human bone marrow-derived mesenchymal stem cells develop nuclei that can move within the cell and form protrusions to contact neighboring cells during neural-like differentiation.

bioRxiv · Jul 27, 2023Cell Biology

Phyllochron duration and changes through rice development shape the vertical leaf size profile

J. P. Pablo, B. Clerget, C. Bueno, J. Dionora, A. J. Domingo, C. C. De Guzman, E. A. Aguilar, N. M. Cadiz, P. C. Sta Cuz

The paper examines how phyllochron duration and changes during rice development influence the vertical leaf size profile across different watering systems and sowing dates.

bioRxiv · Mar 12, 2022 · PreprintPlant Biology

A comprehensive single-cell expression atlas of human AML leukemia-initiating cells unravels the contribution of HIF pathway and its therapeutic potential

T. Velasco-Hernandez, J. L. Trincado, M. Vinyoles, A. Closa, F. Gutierrez-Aguera, O. Molina, V. C. Rodriguez-Cortez, P. Petazzi, S. Beneyto-Calabuig, L. Velten, P. Romecin, R. Casquero, F. Abollo-Jimenez, R. Diaz de la Guardia, P. Lorden, , P. Menendez

The paper creates a single-cell atlas of AML leukemia-initiating cells and shows that targeting the HIF pathway enhances chemotherapy effectiveness against these cells.

bioRxiv · Mar 2, 2022 · PreprintCancer Biology

Transplanting increases the leaf production rate in rice, consequently modifying plant development and growth

B. Clerget, E. Pasuquin, R. Carandang, A. J. Domingo, H. L. Layaoen, C. Bueno

This study shows that transplanting rice increases leaf production rate, modifies plant development and growth, but does not affect grain yield compared to direct-seeding at similar planting density.

bioRxiv · Mar 8, 2021 · PreprintPlant Biology

Electrochemotherapy with bleomycin associated with doxorubicin induces tumor regression and decreases the proliferative index in canine cutaneous squamous cell carcinomas

D. S. Anjos, C. Bueno, L. F. Magalhaes, G. M. Magalhaes, E. Mattos-Junior, M. M. P. Rodrigues, A. B. De Nardi, C. Brunner, A. F. Leis-Filho, S. G. Calazans, C. E. Fonseca-Alves

This study evaluates the effects of electrochemotherapy (ECT) on canine cutaneous squamous cell carcinomas, finding reduced tumor volume and proliferative index but no change in apoptotic markers.

bioRxiv · Jan 11, 2019 · PreprintCancer Biology