Author

F. Gutierrez-Aguera

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

P. Menendez· 2 shared P. Romecin· 2 shared A. Bataller· 1 shared A. Briceno· 1 shared A. Closa· 1 shared A. Fernandez-Trasancos· 1 shared A. Martinez-Moreno· 1 shared Aleg· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

P. Menendez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Generation and proof-of-concept for allogeneic CD123 CAR-Delta One T (DOT) cells in Acute Myeloid Leukemia

D. Sanchez Martinez, N. Tirado, S. Mensurado, A. Martinez-Moreno, P. Romecin, F. Gutierrez-Aguera, D. V. Correia, B. Silva-Santos, P. Menendez

This study generates and pre-clinically validates CD123-targeted CAR-DOTs for relapsed/refractory AML, showing robust cytotoxicity and long-term persistence with IL-15 support.

bioRxiv · Mar 15, 2022Immunology

A comprehensive single-cell expression atlas of human AML leukemia-initiating cells unravels the contribution of HIF pathway and its therapeutic potential

T. Velasco-Hernandez, J. L. Trincado, M. Vinyoles, A. Closa, F. Gutierrez-Aguera, O. Molina, V. C. Rodriguez-Cortez, P. Petazzi, S. Beneyto-Calabuig, L. Velten, P. Romecin, R. Casquero, F. Abollo-Jimenez, R. Diaz de la Guardia, P. Lorden, , P. Menendez

The paper creates a single-cell atlas of AML leukemia-initiating cells and shows that targeting the HIF pathway enhances chemotherapy effectiveness against these cells.

bioRxiv · Mar 2, 2022 · PreprintCancer Biology

Conserved cysteines in titin sustain the mechanical function of cardiomyocytes

E. Herrero-Galan, F. Dominguez, I. Martinez-Martin, C. Sanchez-Gonzalez, N. Vicente, L. Lalaguna, E. Bonzon-Kulichenko, E. Calvo, E. Gonzalez-Lopez, M. Cobo-Marcos, B. Bornstein, A. Briceno, J. P. Ochoa, J. M. Garcia-Aznar, C. Suay-Corredera, , Aleg

The paper identifies that mutations in conserved titin cysteines disrupt mechanoredox control, leading to dilated cardiomyopathy in humans.

bioRxiv · Sep 5, 2020Physiology