D. Alvarez

Constitutive immune surveillance of nasal mucosa by three neutrophil subsets with distinct origin, phenotype, and function

This study identifies three distinct neutrophil subsets in the murine nasal mucosa with unique origins, phenotypes, and functions in immune surveillance.

Chromosome-scale pearl millet genomes reveal a CARLACTONOIC ACID METHYL TRANSFERASE as key determinant of strigolactone pattern and Striga susceptibility

The paper identifies a CLAMT1 gene responsible for strigolactone production and Striga susceptibility in pearl millet by comparing genome assemblies of susceptible and resistant lines.

Admixture with cultivated sunflower likely facilitated establishment and spread of wild sunflower (H. annuus) in Argentina

The paper investigates the invasion history of wild sunflower in Argentina, finding that admixture with cultivated sunflower and genomic selection contributed to its establishment and spread.

Chromatin activity of IκBα mediates the exit from naïve pluripotency

This study shows that IκBα's chromatin activity, not its NF-κB signaling role, is critical for exiting naïve pluripotency in embryonic stem cells.

Functional mRNA delivery to hematopoietic stem and progenitor cells in vivo.

This study demonstrates in vivo delivery of functional mRNA to hematopoietic stem cells (HSC) using lipid nanoparticles, achieving transfection in ~25% of mouse HSC with potential for therapeutic applications.

Monocyte intrinsic NOD2 signalling inhibits pathogenic macrophage differentiation and its loss in inflammatory macrophages improves intestinal inflammation.

This study shows that NOD2 signaling in monocytes inhibits their conversion to pathogenic macrophages and its loss worsens intestinal inflammation.

An outbreak of SARS-CoV-2 in big hairy armadillos (Chaetophractus villosus) associated with Gamma variant in Argentina three months after being undetectable in humans

The paper reports SARS-CoV-2 Gamma variant infection in big hairy armadillos in Argentina three months after its last detection in humans, highlighting potential viral reservoirs.

Independent evolution of influenza A virus H1N1 in pigs in Guatemala

The paper identifies independent evolution of H1N1 influenza A viruses in Guatemalan pigs, showing distinct amino acid signatures and genetic lineage from other Central American H1N1 pdm09 viruses.

Using Unmanned Aerial Vehicles (UAV) for free-roaming dog population size estimation

This study evaluates UAVs for estimating free-roaming dog populations and compares results with capture-recapture and human:dog ratio methods, finding UAVs lack sensitivity but can be improved with timing, area selection, or infrared cameras.

Anatomically remote education of B cells is required for colonic health

This study shows that B cells educated in Peyer's patches are critical for colonic health, as they produce IgA and restrain inflammation in the colon.

Bioactive compounds from Chrysosporium multifidum, a fungus isolated from Hermetia illucens gut microbiota

This study isolates and identifies Chrysosporium multifidum from Hermetia illucens gut microbiota and characterizes six pyrone derivatives and one diketopiperazine with antimicrobial activity against MRSA.