Chromatin activity of IκBα mediates the exit from naïve pluripotency
L. G. Palma, D. Alvarez-Villanueva, M. Maqueda, M. Barrero, A. IGLESIAS, j. Bertran, D. ALVAREZ, C. GARCIA-PRIETO, C. BALLARE, V. RODRIGUEZ-CORTEZ, C. BUENO, A. VIDAL, A. Villanueva, P. Menendez, G. Stik, , A. Bigas
This study shows that IκBα's chromatin activity, not its NF-κB signaling role, is critical for exiting naïve pluripotency in embryonic stem cells.
bioRxiv · Jul 28, 2023Cell Biology