Author

C. C. Hughey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:experimental assay· 4 Assay:metabolomics· 4 Research Focus:metabolism & bioenergetics· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

F. I. Rome· 2 shared P. A. Crawford· 2 shared P. Puchalska· 2 shared A. B. Nelson· 1 shared B. N. Finck· 1 shared B. Viollet· 1 shared D. B. Stagg· 1 shared D. Ferguson· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPhysiology

F. I. Rome

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice

C. C. Hughey, D. P. Bracy, F. I. Rome, M. Goelzer, E. P. Donahue, B. Viollet, M. Foretz, D. H. Wasserman

This study shows that AMPK is necessary for exercise-induced liver adaptations in glycogen and lipid metabolism in mice.

bioRxiv · Sep 1, 2023Physiology

Disruption of Hepatic Mitochondrial Pyruvate and Amino Acid Metabolism Impairs Gluconeogenesis and Endurance Exercise Capacity in Mice

M. R. Martino, M. Habibi, D. Ferguson, R. T. Brookheart, J. P. Thyfault, G. Meyer, L. Lantier, C. C. Hughey, B. N. Finck

bioRxiv · Aug 22, 2023Physiology

Gender-based heterogeneity of FAHFAs in trained runners

A. B. Nelson, L. S. Chow, D. R. Dengel, M. Pan, C. C. Hughey, X. Han, P. Puchalska, P. A. Crawford

The paper compares FAHFA levels in lean and overweight runners, finding gender-based differences and associations with body composition and metabolic factors.

bioRxiv · Jun 7, 2023Physiology

Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice

F. I. Rome, G. L. Shobert, W. C. Voigt, D. B. Stagg, P. Puchalska, S. C. Burgess, P. A. Crawford, C. C. Hughey

This study shows that loss of hepatic PEPCK1 impairs acute exercise glucose regulation but improves liver lipid reduction and muscle mitochondrial adaptations with exercise training in mice.

bioRxiv · Sep 22, 2022Physiology