PhysiologybioRxiv
Disruption of Hepatic Mitochondrial Pyruvate and Amino Acid Metabolism Impairs Gluconeogenesis and Endurance Exercise Capacity in Mice
DOI 10.1152/ajpendo.00258.2023
Author
M. R. Martino
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2020-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- Pharmacology & ToxicologybioRxivPreprint
Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult in mice
N. K. Yiew, J. H. Vazquez, M. R. Martino…·M. R. McGill
This study shows that loss of both MPC and ALT2 increases susceptibility to oxidative stress and worsens liver injury in mice, while ALT2 induction reduces APAP toxicity.
DOI 10.1101/2022.06.14.495517 - PhysiologyCell ReportsPeer-reviewed
Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids
M. R. Martino, M. Gutierrez-Aguilar, N. K. H. Yiew…·B. N. Finck
This study shows that silencing ALT2 in diabetic liver reduces hyperglycemia by decreasing amino acid-derived gluconeogenesis.
- PhysiologybioRxiv
Antisense oligonucleotides against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1
A. J. Lutkewitte, J. M. Singer, T. M. Shew…·B. N. Finck
This study shows that Mogat1 ASOs improve glucose metabolism in mice independently of Mogat1 knockdown or IFNAR-1 activation.
DOI 10.1016/j.molmet.2021.101204