Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes
M. T. Meister, M. J. A. Groot Koerkamp, T. de Souza, W. B. Breunis, E. Frazer-Mendelewska, M. Brok, J. DeMartino, F. Manders, C. Calandrini, H. H. D. Kerstens, A. Janse, M. E. M. Dolman, S. Eising, K. P. S. Langenberg, M. van Tuil, , F. C. P. Holstege
This study generates tumor organoid models of rhabdomyosarcoma subtypes that closely resemble original tumors and can be used for drug screening and genetic modification.
bioRxiv · Jan 3, 2022Cancer Biology