Author

C. Chandler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Evolutionary Biology· 2 Ecology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. bin Sailim· 1 shared A. Burford· 1 shared A. Burt· 1 shared A. Carai· 1 shared A. F. Shenkin· 1 shared A. Mackay· 1 shared A. Martin· 1 shared A. Mastronuzzi· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperEcology

A. bin Sailim

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Reduced effectiveness of purifying selection on new mutations in a parthenogenic terrestrial isopod (Trichoniscus pusillus)

E. Yarbrough, C. Chandler

This study examines mutation accumulation in asexual and sexual isopod species, finding that purifying selection is less effective against new mutations in asexual lineages over long time scales.

bioRxiv · Jan 3, 2023 · PreprintEvolutionary Biology

Evolutionary transition to XY sex chromosomes associated with Y-linked duplication of a male hormone gene in a terrestrial isopod

A. Russell, S. Borrelli, R. Fontana, J. Laricchiuta, J. Pascar, T. Becking, I. Giraud, R. Cordaux, C. Chandler

The paper investigates sex chromosome evolution in Trachelipus rathkei, finding an XX/XY system with Y-linked duplication of a male hormone gene and evidence of Wolbachia influence.

Heredity · Jul 16, 2021Peer-reviewedEvolutionary Biology

Drug screening linked to molecular profiling identifies novel dependencies in patient-derived primary cultures of paediatric high grade glioma and DIPG

D. Carvalho, S. Temelso, A. Mackay, H. Pemberton, R. Rogers, K. Kessler, E. Izquierdo, L. Bjerke, J. Fazal-Salom, M. Clarke, Y. Grabovska, A. Burford, N. Gene-Olaciregui, J. Boult, V. Molinari, , Hubank

bioRxiv · Dec 29, 2020 · PreprintCancer Biology

Epigenetic reprogramming towards mesenchymal-epithelial transition in ovarian cancer-associated mesenchymal stem cells drives metastasis

H. Fan, H. Atiya, Y. Wang, T. Pisanic, J. Wang, I.-M. Shih, K. Foy, L. Frisbie, C. Chandler, H. Shen, L. G. Coffman

This paper shows epigenetic reprogramming of mesenchymal stem cells into CA-MSCs drives ovarian cancer metastasis through partial MET and WT1/EZH2-mediated mechanisms.

bioRxiv · Feb 25, 2020Cancer Biology

The mechanical stability of the worlds tallest broadleaf trees

T. D. Jackson, A. F. Shenkin, N. Majalap, J. bin Jami, A. bin Sailim, G. Reynolds, D. Coomes, C. Chandler, D. Boyd, A. Burt, P. Wilkes, M. Disney

This study examines mechanical stability factors limiting tree height in tall tropical trees, finding that wind damage risk increases with height despite larger diameters, leading to a U-shaped mechanical risk curve.

bioRxiv · Jun 10, 2019Ecology