Labile assembly of a tardigrade protein induces biostasis
S. Sanchez-Martinez, K. Nguyen, S. Biswas, V. Nicholson, A. V. Romanyuk, J. F. Ramirez, S. KC, A. Akter, C. Childs, E. T. Usher, G. M. Ginell, F. Yu, E. Gollub, M. Malferrari, F. Francia, , T. C. Boothby
This study identifies a mechanism by which tardigrade CAHS D proteins form gels to protect cells during desiccation, showing that gelation reduces molecular motion and metabolic activity, with reversible effects.
bioRxiv · Jun 30, 2023Physiology