Author

G. M. Ginell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:multiple species· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. S. Holehouse· 4 shared A. Akter· 1 shared A. Briner· 1 shared A. D. Gitler· 1 shared A. Ekman· 1 shared A. Kundaje· 1 shared A. Obermeyer· 1 shared A. Sanyal· 1 shared

Activity by Year

2023-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersBiophysics

A. S. Holehouse

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Labile assembly of a tardigrade protein induces biostasis

S. Sanchez-Martinez, K. Nguyen, S. Biswas, V. Nicholson, A. V. Romanyuk, J. F. Ramirez, S. KC, A. Akter, C. Childs, E. T. Usher, G. M. Ginell, F. Yu, E. Gollub, M. Malferrari, F. Francia, , T. C. Boothby

This study identifies a mechanism by which tardigrade CAHS D proteins form gels to protect cells during desiccation, showing that gelation reduces molecular motion and metabolic activity, with reversible effects.

bioRxiv · Jun 30, 2023Physiology

Direct prediction of intrinsically disordered protein conformational properties from sequence

J. M. Lotthammer, G. M. Ginell, D. Griffith, R. J. Emenecker, A. S. Holehouse

This paper develops ALBATROSS, a deep learning model that predicts ensemble conformational properties of intrinsically disordered proteins from sequence, enabling proteome-wide analysis.

bioRxiv · May 8, 2023Biophysics

The analytical Flory random coil is a simple-to-use reference model for unfolded and disordered proteins

J. J. Alston, G. M. Ginell, A. Soranno, A. S. Holehouse

The paper introduces the analytical Flory Random Coil (AFRC) model as a reference for unfolded proteins, enabling comparison of experimental and simulation data.

bioRxiv · Mar 12, 2023 · PreprintBiophysics

Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease

S. Boeynaems, X. R. Ma, V. Yeong, G. M. Ginell, J.-H. Chen, J. A. Blum, L. Nakayama, A. Sanyal, A. Briner, D. Van Haver, J. Pauwels, A. Ekman, H. B. Schmidt, K. Sundararajan, L. Porta, , A. D. Gitler

The paper identifies a common toxic mechanism in positively charged peptides across species and develops a machine learning tool to detect it.

bioRxiv · Mar 9, 2023 · PreprintCell Biology