E. W. Martin

Labile assembly of a tardigrade protein induces biostasis

This study identifies a mechanism by which tardigrade CAHS D proteins form gels to protect cells during desiccation, showing that gelation reduces molecular motion and metabolic activity, with reversible effects.

Structural biases in disordered proteins are prevalent in the cell

The paper shows that structural biases in intrinsically disordered proteins persist in human cells and can respond to intracellular changes.

Tardigrade CAHS Proteins Act as Molecular Swiss Army Knives to Mediate Desiccation Tolerance Through Multiple Mechanisms

This study identifies CAHS D as a tardigrade protein that protects against desiccation through multiple mechanisms involving water coordination and slowed molecular motion.

Deciphering how naturally occurring sequence features impact the phase behaviors of disordered prion-like domains

The paper identifies how specific amino acid compositions influence phase separation in prion-like domains and develops a model to simulate these behaviors.

Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation

This study investigates how folded domains of hnRNPA1 modulate phase separation behavior of its disordered low-complexity domain, showing salt-dependent effects through electrostatic interactions and solubility changes.

Protein network structure enables switching between liquid and gel states

The paper uses analytic theory to show how protein interactions determine phase separation behavior, revealing that gel formation is driven by entropy rather than binding energy.