C. D. Nadell

Pseudomonas aeruginosa surface motility and invasion into competing communities enhances interspecies antagonism

This study shows that Pseudomonas aeruginosa uses type IV pili-mediated chemotaxis to invade and disrupt Staphylococcus aureus microcolonies, enhancing interspecies antagonism.

Bacteriophage diet breadth is impacted by interactions between bacteria

The paper models and experiments on how bacterial interactions influence bacteriophage diet breadth, finding that competition favors generalists while mutualism favors specialists.

Community composition and the environment modulate the population dynamics of type VI secretion in human gut bacteria

The paper shows that T6SS in B. fragilis is lost in adults but can be favored or disfavored in mice depending on community composition and ecological conditions.

Multispecies biofilm architecture determines bacterial exposure to phages

This study shows that multispecies biofilm architecture affects phage exposure and community dynamics in E. coli and V. cholerae co-cultures.

Breakdown of clonal cooperative architecture in multispecies biofilms and the spatial ecology of predation

The paper investigates how predator-prey dynamics between Vibrio cholerae and Escherichia coli in biofilms affect their spatial structure and survival under Bdellovibrio bacteriovorus predation.

Social evolution of shared biofilm matrix components

This study shows that shared diffusible biofilm matrix proteins in Vibrio cholerae are susceptible to cheater exploitation, and their evolutionary stability depends on spatial structure, sharing mechanisms, and environmental flow conditions.

An Alanine Aminotransferase is Required for Polysaccharide Regulation and Resistance of Aspergillus fumigatus Biofilms to Echinocandin Treatment

This study shows that alanine aminotransferase AlaA is essential for A. fumigatus biofilm formation and resistance to echinocandin antifungals, with its inhibition increasing drug susceptibility.

Differential surface competition and biofilm invasion strategies of Pseudomonas aeruginosa PA14 and PA01

This study compares the biofilm colonization strategies of Pseudomonas aeruginosa PA14 and PAO1, showing PAO1 outcompetes PA14 during initial colonization but PA14 excels in invading pre-formed biofilms and surviving starvation.

A heterogeneously expressed gene family modulates biofilm architecture and hypoxic growth of Aspergillus fumigatus

This paper identifies a gene family in Aspergillus fumigatus that modulates biofilm architecture and hypoxic growth, with potential applications in clinical and industrial settings.

Pseudomonas aeruginosa and Candida albicans both accumulate greater biomass in dual species biofilms under flow

This study shows that Pseudomonas aeruginosa and Candida albicans accumulate more biomass in dual-species biofilms under flow compared to single-species biofilms.

Predation by Bdellovibrio bacteriovorus transforms the landscape and community assembly of bacterial biofilms

This study shows that Bdellovibrio bacteriovorus preys on Vibrio cholerae biofilms up to a maturation threshold, altering biofilm structure and community assembly.

Biofilm structure promotes coexistence of phage-resistant and phage-susceptible bacteria

The paper uses simulations and experiments to show that biofilm structure promotes coexistence of phage-resistant and phage-susceptible bacteria compared to planktonic cultures.

BiofilmQ, a software tool for quantitative image analysis of microbial biofilm communities

BiofilmQ is a software tool that enables automated, high-throughput quantitative analysis of 3D and 2D microbial biofilm communities through image cytometry.

Filamentation of Vibrio cholerae is an adaptation for surface attachment and biofilm architecture

This study shows that filamentous Vibrio cholerae cells have an advantage in colonizing chitin particles but are outcompeted by matrix-secreting variants in long-term biofilm formation.

Cellular advective-diffusion drives the emergence of bacterial surface colonization patterns and heterogeneity

The paper shows fluid flow represses mixing of bacterial clonal lineages in biofilms, influencing species interactions and evolution through cellular transport mechanisms.

Cell adhesion and fluid flow jointly initiate genotype spatial distribution in biofilms

This study investigates how cell adhesion and fluid flow influence genotype spatial distribution in biofilms using Vibrio cholerae, finding that adhesion can both increase and decrease clonal cluster size depending on environmental conditions.