Author

C. De Santi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Organism:human· 5 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

C. Sala· 6 shared I. Paciello· 6 shared R. Rappuoli· 6 shared E. Andreano· 5 shared E. Montomoli· 5 shared G. Piccini· 5 shared N. Manganaro· 5 shared P. Pileri· 5 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

6 shared papersImmunology

C. Sala

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Anti-capsule human monoclonal antibodies protect against hypervirulent and pandrug-resistant Klebsiella pneumoniae

E. Roscioli, V. Zucconi Galli Fonseca, S. S. Bosch, I. Paciello, G. Maccari, G. Batani, S. Stazzoni, G. Cardinali, G. Tiseo, C. Giordano, Y. Shen, L. Capoccia, M. Ridelfi, M. Troisi, N. Manganaro, , R. Rappuoli

This study isolates human monoclonal antibodies against hypervirulent, pandrug-resistant Klebsiella pneumoniae and identifies capsule-specific antibodies as protective against bloodstream infection.

bioRxiv · Feb 14, 2024 · PreprintMicrobiology

mRNA vaccines and hybrid immunity use different B cell germlines to neutralize Omicron BA.4 and BA.5

E. Andreano, I. Paciello, G. Pierleoni, G. Maccari, G. Antonelli, V. Abbiento, P. Pileri, L. Benincasa, G. Giglioli, G. Piccini, C. De Santi, C. Sala, D. Medini, E. Montomoli, P. Maes, R. Rappuoli

The paper compares neutralizing antibodies against Omicron BA.4 and BA.5 from mRNA-vaccinated individuals and those with hybrid immunity, finding differences in epitope targeting and B cell germlines used.

bioRxiv · Aug 4, 2022 · PreprintImmunology

COVID-19 mRNA third dose induces a unique hybrid immunity-like antibody response

E. Andreano, I. Paciello, G. Pierleoni, G. Piccini, V. Abbiento, G. Antonelli, P. Pileri, N. Manganaro, E. Pantano, G. Maccari, S. Marchese, L. Donnici, L. Benincasa, G. Giglioli, M. Leonardi, , R. Rappuoli

This study examines how a third mRNA vaccine dose enhances neutralizing antibody responses against SARS-CoV-2 variants by expanding specific B cell germlines and altering the antibody repertoire.

bioRxiv · May 9, 2022 · PreprintImmunology

Hybrid immunity improves B cell frequency, antibody potency and breadth against SARS-CoV-2 and variants of concern

E. Andreano, I. Paciello, G. Piccini, N. Manganaro, P. Pileri, I. Hyseni, M. Leonardi, E. Pantano, V. Abbiento, L. Benincasa, G. Giglioli, C. De Santi, M. Fabbiani, I. Rancan, M. Tumbarello, , R. Rappuoli

This study compares B cell responses in naive and convalescent individuals after SARS-CoV-2 vaccination, showing convalescents have higher frequency and broader neutralizing antibody responses against variants.

bioRxiv · Aug 12, 2021 · PreprintImmunology

Extremely potent human monoclonal antibodies from convalescent Covid-19 patients

E. Andreano, E. Nicastri, I. Paciello, P. Pileri, N. Manganaro, G. Piccini, A. Manenti, E. Pantano, A. Kabanova, M. Troisi, F. Vacca, D. Cardamone, C. De Santi, L. Benincasa, C. Agrati, , R. Rappuoli

The paper isolates extremely potent human monoclonal antibodies from convalescent Covid-19 patients, effective against SARS-CoV-2 at low concentrations.

bioRxiv · Oct 7, 2020Immunology

Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients

E. Andreano, E. Nicastri, I. Paciello, P. Pileri, N. Manganaro, G. Piccini, A. Manenti, M. Troisi, F. Vacca, E. Pantano, C. De Santi, D. Cardamone, A. Kabanova, C. Agrati, C. Castilletti, , R. Rappuoli

The paper isolates neutralizing human monoclonal antibodies from Covid-19 convalescent patients for therapeutic and prophylactic interventions.

bioRxiv · May 5, 2020 · PreprintImmunology