Author

C. Dugast-Darzacq

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

E. Van Dis· 2 shared E. Wehri· 2 shared J. Schaletzky· 2 shared L. H. Yamashiro· 2 shared X. Nguyenla· 2 shared A. W. Roberts· 1 shared C. C. Ward· 1 shared D. Dovala· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

E. Van Dis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiophysicsbioRxivPreprintFeb 8, 2021

Structure of the human SAGA coactivator complex

E. Nogales, D. Herbst, M. Esbin…·R. Tjian

The paper presents the 2.9 Å structure of the human SAGA coactivator complex, revealing unique structural features and functional modules with implications for transcription and splicing in disease and cancer.

DOI 10.1101/2021.02.08.430339

humanstructural biology

𝕏 PostBluesky

MicrobiologybioRxivDec 30, 2020

Screening a library of FDA-approved and bioactive compounds for antiviral activity against SARS-CoV-2

S. B. Biering, E. Van Dis, E. Wehri…·S. A. Stanley

This study screens FDA-approved compounds for antiviral activity against SARS-CoV-2 and identifies 13 effective compounds, including seven new candidates and one synergistic combination with remdesivir.

DOI 10.1021/acsinfecdis.1c00017

humanexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivSep 18, 2020

Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells

X. Nguyenla, E. Wehri, E. Van Dis…·J. Schaletzky

This study identifies 20 approved drugs that synergize with remdesivir to inhibit SARS-CoV-2 replication in human lung cells, with HCV NS5A inhibitors showing the strongest effects.

DOI 10.1038/s41598-022-21034-5

humanbulk RNA-seq

𝕏 PostBluesky