A. W. Roberts

Early cytokine-driven adaptation of survival pathways in lymphoid cells during targeted therapies

This study shows that CLL cells rapidly adapt to venetoclax by upregulating pro-survival proteins and cytokines, suggesting combination therapies targeting these pathways could improve treatment outcomes.

Cellulose synthase-like D (CSLD) proteins move in the plasma membrane and their targeting to cell tips, but not cell plates, depends on the actin cytoskeleton

This study investigates CSLD6 movement in moss protonemata, showing it traffics in the plasma membrane and localizes to cell tips, with actin-dependent apical delivery, distinct from CESA10 behavior.

Screening a library of FDA-approved and bioactive compounds for antiviral activity against SARS-CoV-2

This study screens FDA-approved compounds for antiviral activity against SARS-CoV-2 and identifies 13 effective compounds, including seven new candidates and one synergistic combination with remdesivir.

Global proteomic profiling of primary macrophages during M. tuberculosis infection identifies TAX1BP1 as a mediator of autophagy targeting

The paper uses proteomic analysis to identify TAX1BP1 as a mediator of autophagy targeting M. tuberculosis during macrophage infection.

Resident Macrophages are Locally Programmed for Silent Clearance of Apoptotic Cells

The paper identifies macrophages that silently clear apoptotic cells by expressing AC receptors and limiting nucleic acid responses, showing that tissue cues program this behavior.